Home » Infant Reflux Main » Treating Infant Reflux and Pediatric GERD » Medications » Pepcid - Famotidine

Pepcid (famotidine) for Treating Infant Reflux and GERD

   
Rachel McMahon, B.Sc. Chem. Min. Sc.
January 2007
 

  
 

PREPARATIONS:

Oral Suspension: is a smooth, mobile, off-white, homogeneous suspension with a cherry-banana-mint flavor, containing 40 mg of famotidine per 5 ml (8mg/ml)

Chewable Tablet: not recommended for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.

Tablet: 10, 20, 40mg

Capsule: 10mg
 

THINGS TO BE AWARE OF:

  • Famotidine is a histamine H2 antagonist. It works by reducing acid in the stomach by blocking one of the chemicals (histamine) that stimulates the production of stomach acid.
  • If you are sensitive to or have ever had an allergic reaction to Famotidine, or a comparable H2 blocker, you should not take Famotidine. Make sure your doctor is aware of any drug reactions experienced.
  • Do not take antacids within 1 hour of taking famotidine. Antacids may decrease the effectiveness of famotidine, more so than ranitidine.
  • Suspension should be prepared at the time of dispensing, and lasts 30 days.
  • Shake the Pepcid suspension vigorously for 5 to 10 seconds before measuring a dose. To ensure that you get the correct dose, use a dose-measuring cup or spoon, not a regular table spoon to measure a dose of the suspension. If you do not have a dose-measuring device, ask your pharmacist for one.
  • Famotidine is very weight sensitive and should be adjusted regularly with weight gain.
  • It is best to space this med an hour either side of a PPI i.e. prevacid or prilosec, as it may interfere with absorption but also be too hard on a child’s stomach all that once.
  • May be taken with or without food, though most prefer to administer it 30mins before feeding

STORAGE:

Store famotidine at room temperature away from moisture, heat, and light. Do not store in the bathroom. Discard any unused Pepcid Suspension after 30 days.

PEDIATRIC DOSING:

Famotidine 40mg/5ml (or 8mg/ml)
Patients less than 3months of age 0.5mg/kg once per day
Patients over 3 months of age 0.5mg/kg twice per day

OTHER USES:

Treatment of erosive esophagitis, duodenal ulcers and gastric ulcers. Also maintenance of healing of duodenal and gastric ulcers.

DRUG INTERACTIONS:

Do not take antacids within 1 hour of taking famotidine. Antacids may decrease the effectiveness of famotidine.

Anticoagulants (e.g., warfarin), beta-blockers (e.g., propranolol), bupivacaine, ethanol, hydantoins (e.g., phenytoin), nifedipine, procainamide, sulfonylureas (e.g., glipizide), theophylline, or triazolam because the actions and side effects of these medicines may be increased.
Sucralfate, (carafete) Nondepolarizing muscle relaxants (e.g., vecuronium) because the effectiveness of famotidine may be decreased.
 

SIDE EFFECTS:

Constipation; diarrhea; dizziness; drowsiness; headache; nausea; sleeplessness; stomach pain; vomiting
 

 

 


 

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Site Last Modified: March 29, 2007
*Disclaimer: The information available on this website should not be used as a substitute for professional medical care for the prevention, diagnosis, or treatment of your child's reflux. Please consult with your child's doctor or pharmacist before trying any medication (prescription or OTC) or following any treatment plan mentioned. This information is provided only to help you be as informed as possible about your child's condition.
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